|Amanda De Santa|
|Voice||Vicki Van Tassel|
Amanda is Michael's wife. Together they have two children, James and Tracey. Although Amanda and Michael always had a good marriage, the last couple of years their relationship has changed and they can't outstand each other. At some point, Amanda cheats on Michael, when she sleeps with another man.
- According to Trevor, Amanda's breasts are fake.
- It is probably possible to play minigames, such as tennis, with Amanda.